Music Pen
One of the games my grandparents had on their computer in Gold Beach, OR. Structurally an adventure game, though I didn't realize that at the time - it did have lots of fun clickable hotspots like the Humongous Entertainment games. I remember going back to the heart minigame a lot, which was a pinball table all about moving blood cells between the chambers of the heart.
Over the years I had brief encounters with other Magic School Bus games, but this is the only one I played for any length of time.